Bioreactors For Animal Cell Culture Slideshare

This process can either be aerobic or anaerobic these bioreactors are commonly cylindrical ranging in size from litres.

Bioreactors for animal cell culture slideshare.

The production of monoclonal antibodies on a laboratory scale. Bioreactors the state of the art prof dr said saad soliman by ahmed shehata ali gail 2. Adherent cell types bind to the hollow fibers and deposit their extracellular matrix and cellular. A bioreactor refers to any manufactured device or system that supports a biologically active environment.

At high cell densities the culture will be viscous and difficult to mix in airlift bioreactor. The extant bioreactors work well for cells that float such as the hemopoietic cells in which starling flow can adequately provide gases and nutrients but are limited in their utility for adherent cell types derived from solid tissues or organs. In one case a bioreactor is a vessel in which a chemical process is carried out which involves organisms or biochemically active substances derived from such organisms. Definitions 1 bioreactor is a vessel in which a chemical process is carried out which involves organisms mainly microbes viruses or bacteria fungi and yeasts traditionally designated as fermenters or biochemically active substances enzymes e g derived from such organisms.

However for its particular nature viscosity of plant cell is low and mixing in airlift bioreactors is not greatly affected by biomass up to 40gl 1 formation of dead zones where conditions are anoxic and cells settle out is a problem.